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Trimethoprim
Characterised impurities
| Impurity | Chemical name | Pharmacopoeia |
|---|---|---|
| Impurity “I” TMBA | 3-(phenylamino)-2- (3,4,5- trimethoxybenzyl)pr op-2-enenitrile 3,4,5-Trimethoxy benzaldehyde | BP/EP BP/EP |
| Impurity "A" (EP) / Related Compound "E" (USP) | 4-(3- Methylphenyl)-2H- pyrido[4,3-e]-1,2,4- thiadiazin-3-(4H)-one 1,1-dioxide; (4-m- tolyl-2H-pyrido[4,3- e)[1,2,4]thiadiazin-3- (4H)-one 1,1-dioxide | EP/USP |
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