Tofacitinib

Route - KSMs and intermediates

1. KSMN,4-Dimethyl-1-(phenylmethyl)-3-piperdinamine hydrochloride1062580-52-2
2. KSM4-Chloro-7H-pyrrolopyrimidine3680-69-1
3. KSMEthylcyanoacetate105-56-6
4. Intermediatebis-N-(3R,4R)-(1-Benzyl-4-methylpiperidin-3- yl)methylamine ditolouyl tartarate477600-71-8
5. Intermediate4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]-pyrimidine479633-63-1
6. Intermediate((3R,4R)-(1-Benzyl-4-methylpiperidin-3-yl)methyl- (7-tosyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl))amine923036-30-0
7. Intermediate((3R,4R)-(1-Benzyl-4-methylpiperidin-3-yl)methyl- (7H-pyrrolo[2,3-d]pyrimidine-4-yl)amine477600-73-0
8. IntermediateN-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H- pyrrolo[2,3-d]pyrimidin-4-amine477600-74-1