PRODUCT CATALOG
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Telmisartan
Human APIstandards in stock
Route - KSMs and intermediates
- KSM4-methyl-2-propyl-1H-benzo[d]imidazole-6- carboxylic acid152628-03-0
- KSMN-Methyl-O-phenylene Diamine Dihydrochloride25148-68-9
- KSM2-Cyano-4-Bromo Methyl Biphenyl114772-54-2
- Intermediate4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2- propyl-1H-benzimidazole152628-02-9
- Intermediate4'-[[4-methyl-6-(1-methyl-1H-benzimidazol-2- yl)-2-propyl-1H-benzimidazol-1-yl]methyl][1,1'- biphenyl]-2-carbonitrile144702-27-2
Impurity and working standards - ready stock
| Structure | Standard | CAS | Availability | |
|---|---|---|---|---|
 | 3-Methyl-4-Nitrobenzoic acid (MNBA) | 3113-71-1 | In stock | |
 | N-methyl-ortho- phenylenediamine dihydrochloride (NMOPDA) | 25148-68-9 | In stock | |
 | Methyl Propyl Benzimldazole Carbcxylic Acid (MPBCA) | 152628-03-0 | In stock | |
 | 2-n-propyl-4-methyl-6-(1- methyl benzimidazole-2-yl) benzimidazole (BIM) | 152628-02-9 | In stock | |
 | 2-Cyano-4- bromomethybiphel(OTBB) | 114772-54-2 | In stock | |
 | Condensed Product(BICBP) | 144702-27-2 | In stock | |
 | 3-methyl-4-Butyramide-5- nitrobenzoate[MBNB) Methyl 3-amino-4- butyramido-5- methylbenzoate | 152628-01-8 | In stock | |
| Telmisartan | 144701-48-4 | In stock | |
 | 4-(3'-Methylphenyl)amino-3- pyridine sulphonamide (MTPS) | 72811-73-5 | In stock | |
 | 4-Methylbiphenyl-2- carboxylic acid Methyl Ester ( OTBA Methyl ester) | 114772-34-8 | In stock |
Characterised impurities
| Impurity | Chemical name | Pharmacopoeia |
|---|---|---|
| Impurity "B" | 4'-[[7-methyl-5-(1- methyl-1- benzimidazol-2-yl)-2- propyl-1- benzimidazol-1- yl]methyl][1,1'- biphenyl]-2- carboxylic acid | EP |
| Impurity “C” i.e. Telmisarta n tert- butyl ester | 1,1-dimethylethyl 4¢-[[4-methyl-6-(1- methyl-1H- benzimidazol-2-yl)-2- propyl- 1Hbenzimidazol-1- yl]methyl]biphenyl- 2-carboxylate, | EP/USP |
| Impurity “E” i.e. Telmisarta n diacid | 1-[(2- carboxybiphenyl-4- yl)methyl]-4-methyl- 2-propyl-1H- benzimidazol-6- carboxylic acid, | BP/EP |
| Impurity “F” i.e. Telmisarta n Amide | 4-[[4-methyl-6-(1- methyl-1H- benzimidazol-2-yl)-2- propyl-1H- benzimidazol-1- yl]methyl]biphenyl- 2-carboxamide, | BP/EP |
| Impurity “G” | 4-[[4-methyl-6-(1- methyl-1H- benzimidazol-2-yl)-2- propyl-1H- benzimidazol-1- yl]methyl]biphenyl- 2-carbonitrile | BP/EP |
| Impurity "J" | 4'-[(5-Chloro-1,7'- dimethyl-2'-propyl- 1H,3'H-[2,5'- bibenzimidazol'-3'- yl)methyl][1,1'- biphenyl]-2- carboxylic acid | EP |
| Impurity "I" (Methyl Ester) “MBMN” (Intermedi ate) | Methyl-4’-((1,7’- dimethyl-2’-propyl- 1H,3’H-[2,5’- bibenzo[d]imidazol]- 3’-yl)methyl-[1,1’- biphenyl]-2- carboxylate Benzoic acid, 3- methyl-5-nitro-4-[(1- oxobutyl)amino]- methyl ester | EP IHT |
| MBMA “BIMC ” (Intermedi ate) NMOPDA.2 HCl | 3-Methyl-4- Butyramide-5-Amino Benzoate 2-n-propyl-4- methyl-1H- benzimidazole-6- carboxylic acid N-Methyl-o- phenlenediamine dihydrochloride | Aug… IHT IHT |
| OTBA Methyl ester OTBBE Ortho toluyl benzoic acid (OTBA) Ortho tolyl Benzo Nitrile (OTBN) OTBA Amide | Methyl 4’-methyl- [1,1’-biphenyl]-2- carboxylate Orthotolyl benzyl butyl ester Butyl-4’- methyl-(1,1’- biphenyl)-2- carboxylate 4’-methyl-(1,1’- biphenyl)-2- carboxylic acid 2-Cyano-4’-methyl- biphenyl 4’-methyl-[1,1’- biphenyl]-2- carboxamide | IHT IHT IHT IHT IHT |
| OTBB (Bromo OTBN) Telmisarta n "F" i.e. Telmisarta n amide | 4’-[(1,7’-dimethyl-2’- propyl-1H,3’H-2,5’- bibenzo[d]imidazol- yl)methyl]biphenyl- 2-carboxamide | IHT USP/EP |
| Impurity "H" | 1,1-dimethylethhyl- (brompmethyl)biphe nyl-2-carboxylate | EP |
| Bromo ester Methyl propyl benzimida zole Carboxylic acid Methylpro pyl benzimida zole methyl ester 3-Methyl- 4- Nitrobenz oic acid | Methyl 4’- (bromomethyl)-[1,1’- biphenyl]-2- carboxylate 4-methyl-2-propyl- 1H- benzo[d]imidazole- 6-carboxylic acid (KSM-A) Methyl-4-methyl-2- propyl-1H- benzimidazole -6- carboxylic acid methyl ester 3-Methyl-4- Nitrobenzoic acid | IHT IHT IHT IHT |
| N-Hydroxy Compound Telmisarta n Di acid i.e. impurity "E" 3-Methyl- 4-amino benzoate 3-Methyl- 4-nitro benzoate | 1-hydroxy-4-methyl- 2-propyl-1H- benzo[d]imidazole- 6-carboxylic acid ((2’-carboxy-[1,1’- biphenyl]-4- yl)methyl)-4-methyl- 2-propyl-1H- benzo[d] imidazole- 6-carboxylic acid 3-Methyl-4-amino benzoate 3-Methyl-4-nitro benzoate | IHT IHT IHT IHT |
| 3-Methyl- 4- Butyramid e-5-Nitro Benzoate 3-Methyl- 4- Butyramid e-5-Amino Benzoate Bromo OTBBE | 3-Methyl-4- Butyramide-5-Nitro Benzoate 3-Methyl-4- Butyramide-5-Amino Benzoate Buty;-4’- (bromomethyl)-(1,1’- biphenyl)-2- carboxylate | IHT IHT IHT |
| Methyl ester of N- hydroxy compound | Methyl-1-hydroxy-4- methyl-2-propyl-1H benzo [d] imidazole- 6-carboxylate | IHT |
| 1-chloro-2- Nitrobenze ne BICBP | 1-chloro-2- Nitrobenzene 2-Cyan-4'-[2-n- propyl-4-methyl-6- methylbenzimidazol e-2yl)benzimidazole- 1-ylmethyl]biphenyl | IHT IHT |
| Regio Cyano Telmisarta n/ Regio BICBP | 4'-[[7 -methyl-5-{1 ~rilethyl-1 H- benzil11id~:zole-2- yl)-2-propyl-1 Hbenzimidazoie-1- yljmethyl]biphenyl- 2-carbonitrile | IHT |
| Butyryl chloride Methyl-4- butyramid o-3- | Butanoyl chloride Methyl-4- butyramido-3- | IHT IHT |
| methylben zoate N-Methyl- 2- nitroanilin e | methylbenzoate N-Methyl-2- nitroaniline | IHT |
| Impurity “C” | 2,4-Diamino-α-(3,4,5- trimethoxy phenyl)-5- pyrimidinemethanol | EP |
| Impurity “J” | 3,4,5- trimethoxybenzoic acid, | BP/EP |
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