PRODUCT CATALOG
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Simvastatin
standards in stock
Impurity and working standards - ready stock
| Structure | Standard | CAS | Availability | |
|---|---|---|---|---|
| Lovastatin | 75330-75-5 | In stock | ||
| AMS | 139893-43-9 | In stock | ||
| Simvastatin | 79902-63-9 | In stock | ||
| EOL | 1426129-50-1 | In stock |
Characterised impurities
| Impurity | Chemical name | Pharmacopoeia |
|---|---|---|
| "THL" IMPURITY | hydroxy-2'(S)6'(R)- dimethyl- 1.2.6.7.8,8a'(R)hexah ydronaphthyl-1'- (S)ethyl]4(R)- (dimethyl tertbutylsilyoxy)-3,4, 5,6-tetrahydro-2H- pyran-2-one | IHT |
| "Triol Acid" impurity | [1',2',6',7',8',8a'(R)hex ahydro-2'(S)6'(R)- dimethyl- 8'(S)hydroxy-1'(S)- naphthyl]-3(R)5(R)- dihydroxyheptanoic acid | IHT |
| "DL" impurity Lova Potassium salt "PSVF" impurity | 6(R)-[2-(8'(S)- hydroxy-2'(S),6'(R)- dimethyl- 1,2,6,7,8,8a(R)- hexahydronaphthyl]- 1'-(S))ethyl]-4(R)- hydroxy-3,4,5,6- tetrahydro-2H- pyran-2-one (3R,SR)-7- [C1S,2S,6R,8S,8aR)-8 -[(2- methylbutanoyl)oxy] -2,6-dimethyl- 1,2,6,7,8a-hexa hydronaphthalen-1- yl)]-3,5- dihydroxyheptanoic acid potassium salt 6(R)-[2-(8'(S)-2',2'- dimethylbutyryloxy- 2'(S),6'(R)-dimethyl- 1,2,6,7,8,8a(R)- hexahydronaphthyl- 1'-(S))ethyl]-4(R)- (dimethyl- tetrbutylsilyloxy)3,4, 5,6-tetra02H-pyran- 2-one | IHT IHT IHT |
| Cyclic Impurity | (3R,5S)-5-([1,1'- biphenyl]-4- methyl)-3-methyl pyrrolidine-2-one 2-Methylpropan-2- | IHT |
| Sac. Maleic Imp. | aminium-(Z)-4- ((2S,4R)-1-([1,1'- biphenyl'-4-yl)5- ethoxy-4-methyl-5- oxopentan-2- yl)amino)-4-oxobut- 2-enolate | IHT |
| "Diacid" impurity | (2R,4S)-5-([1,1'- biphenyl]-4-yl)-4-(3- carboxypropanamid o)-2- methylpentanoic acid | IHT |
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