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Piperaquine Phosphate
Human API
Characterised impurities
| Impurity | Chemical name | Pharmacopoeia |
|---|---|---|
| “PPQ-1” “Chloro Compound ” | “DIMER” 7-Chloro-4-1- piperazinyl-quinoline 7-chloro-4-{4-(3- chloropropyl)piperaz in-1-yl}quinoline | IHT IHT IHT |
| Impurity “B” i.e. Related compound “A” | 4-hydroxy-7- chloroquinoline (3S,4R)-3-[(1,3- benzodioxol-5- yloxy)methyl]-4-(4- methoxyphenyl) | IHT BP/EP/ USDMF /USP |
| Impurity “C” | (3S,4R)-3-[(1,3- benzodioxol-5- yloxy)methyl]-1- benzyl-4-(4- fluorophenyl)pipera (-)-N-benzyl paroxetine | EP |
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