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Paroxetinehcl

Characterised impurities

ImpurityChemical namePharmacopoeia
Impurity "D"/Relate d compound "C"(3R,4S)-3-[(1,3- benzodioxol-5- yloxy)methyl]-4-(4- fluorophenyl]piperid hydrochloride ((+)-Trans pParoxetine HClEP/BP/ USP
Impurity “G” i.e. Related compound “E”4-(4-fluorophenyl)-1- methyl-1,32,3,6- tetrahydropyridine)EP/USP
Related Compound "F" (-)Carbinol "MesitylTrans(-)-1-methyl-3- [1,3-benzodioxol-5- yloxy)methyl]-4-(4- fluorophenyl) piperidine;(N-Methyl paroxetine) Trans-4-(4’- Fluorophenyl)-3- hydroxy methyl-1- methylpiperidine [(3S,4S)-4-(4- fluorophenyl)-1- methylpiperidin-3-USP IHT IHT
Carbinol" 3,4- (Methylen edioxy) phenylace tate Sesamolyl)methyl methanesulfonate 3,4- (methylenedioxy)ph eny acetate; Benzo[d][1,3]dioxol- 5-yl)acetate 1,3-Benzodioxol-5-ol; 2H-1,3-benzodioxol- 5-olIHT IHT
Carbamatetrans-4-(4- fluorophenyl)-3-(3,4- methylenedioxyphen oxymethyl)-1- phenoxycarbonyl piperidineUSDMF
Impurity “A”(2RS)-3- (naphthalene-1- yloxy)propane-1,2- diolBP/EP/ USDMF

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