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Olanzapine

Human API

Characterised impurities

ImpurityChemical namePharmacopoeia
Related compound “C”2-methyl-4-(4- methylpiperazin-1- yl)-10H-benzo[b] thieno[2,3-e] [1,4]diazepine 4’-N- oxide)EP/USP
Related compound “D” “Desmethy l”2-methyl-4-(4- methyl-4- oxidopiperazin-1- yl)-10OH-tieno — (2,3b) (1,5) benzodiazepine 2-Methyl-4-(1- piperazinyl)-1 OH- thieno (2,3-b] [1,5jbenzodiazepinEP IHT
“AMC” (Intermedi ate)2-Amino -5-methyl thiophene-3- carbonitrileEP
AMB2-(2- Aminophenylamino)- 5-methylthiophene- 3-carbonitrileIHT

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