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Losartan Potassium

Human APIstandards in stock

Route - KSMs and intermediates

  1. KSMOrtho tolyl benzo nitrile157366-46-6
  2. KSM2-Butyl-4-chloro-5-formyl imidazole83857-96-9
  3. Intermediate4-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H- imidazole-1-yl]methyl}biphenyl-2- Carbonitrile.114772-55-3
  4. Intermediate(2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5- yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol114798-26-4

Impurity and working standards - ready stock

StructureStandardCASAvailability
Structure of Losartan BaseLosartan Base114798-26-4In stock
Structure of Losartan PotassiumLosartan Potassium124750-99-8In stock

Characterised impurities

ImpurityChemical namePharmacopoeia
Impurity “C”[2-butyl-5-chloro-1- [[2’-(1H-tetrazol-5- yl)biphenyl-4-yl] methyl]-1H-imidazol- 4-yl]methanolBP/EP/ UDMF
Impurity “D”2-butyl-4-chloro-1H- imidazole-5- carbaldehydeBP/EP
Impurity “E”5-(4’- methylbiphenyl-2- yl)-1H-tetrazoleBP/EP
Impurity “F”5-[4’-[[2-butyl-4- chloro-5-[[(1- methylethyl)oxy] methyl]-1H-imidazol- yl]methyl]biphenyl- 2-yl]-1H-tetrazoleBP/EP
Impurity “G”Triphenylmethanol [2-butyl-4-chlkoro-1-BP/EP
Impurity “H”[[2’-[2- (triphenylmethyl)-2H -tetrazol-5- yl]biphenyl-4- yl]methyl]-1H- imidazol-5- yl]methanolBP/EP
Impurity "I"5-[4'-[[2-butyl-4- chloro-5- [[(triphenylmethyl]o xy]-methyl]-1H- imidazol-1- yl]methyl]biphenyl- 2-yl]-1H-tetrazoleBP/EP
Impurity “J”[2-butyl-4-chloro-1- [[2’-(1H-tetrazol-5- yl)biphenyl-4-yl] methyl]-1H-imidazol- 5-yl]methyl acetateBP/EP/ USDMF
Impurity “K”2-butyl-4-chloro-1- [[2’(1H-tetrazol-5- yl)biphenyl-4-yl] methyl]-1H-imidazol- 5-carbaldehydeBP/EP/ USDMF
Impurity “M”[2-butyl-1-[[2’-[2-[[2- butyl-4-chloro-1-[[2’- (1H-tetrazol -5-yl) biphenyl-4- yl]methyl]1H- imidazol-5- yl]methyl]2H- tetrazol-5- yl]biphenyl-4- yl]methyl]-4-chloro- 1H-imidazol-5-(EP)
Condense d Mass Losartanyl]methanol 4’-((2-butyl-4-chloro- 5-formyl-1H- imidazol-1- yl)methyl)-[1,1’- biphenyl]-]2- carbonitrileIHT
N-Nitroso diethyl amine (NDEA)N-Nitroso diethyl amineIHT
NDMA MethylNitrosodimethylami 5-(4'-((2-butyl-4- chloro-5- (methoxymethyl)-1HIHT IHT
ether Azide impurity of BCFI-imidazol-1- yl)methyl)[1,1'- biphenyl]-2-yl)-1H- tetrazole 5-(Azidomethyl)-2- butyl-4-chloro-1H- imidazoleIHT
Azide impurity of OTBB2-[4- (Azidomethyl)phenyl ]benzonitrileIHT
Diphenyl Related Impurity(([1,1’-biphenyl]-4,4’- diylbis(methylene))bi s(2-butyl-4-chloro- 1H-imidazole-1,5- diyl))dimethanolIHT
"Azide" impurity of Losartan5-[4'-[[5- (azidomethyl)-2- buttyl-4-chloro-1H- imidazole-1- yl]methyl[1,1'- biphenyl]-2-yl]-2H- tetrazoleIHT
"Azide" impurity of Losartan Intermedia te-I Dibromo OTBN "Amine" impurity of Losartan4'((5-Azidomethyl)-2- butyl-4-chloro-1H- imidazol-1- yl)methyl-[1,1'- biphenyl-2- carbonitrile 2'-Cyano-4- dibromomethyl)biph enyl 5-(4-((5- (aminomethyl)-2- butyl-4-chloro-1H- imidazol-1- yl)methyl)-[1,1- biphenyl]-2-yl)-1H- tetrazoleIHT IHT
NDBANitrosodibutylamineIHT
Intermedia te-I4’-((2-butyl-4-chloro- 5-(hydroxyl methyl)1H-imidazol- yl)methyl)biphenyl- 2-carbonitrileIHT
Impurity “A”(trifluoromethyl)aniliBP/US P

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