PRODUCT CATALOG
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Losartan Potassium
Human APIstandards in stock
Route - KSMs and intermediates
- KSMOrtho tolyl benzo nitrile157366-46-6
- KSM2-Butyl-4-chloro-5-formyl imidazole83857-96-9
- Intermediate4-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H- imidazole-1-yl]methyl}biphenyl-2- Carbonitrile.114772-55-3
- Intermediate(2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5- yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol114798-26-4
Impurity and working standards - ready stock
| Structure | Standard | CAS | Availability | |
|---|---|---|---|---|
| Losartan Base | 114798-26-4 | In stock | ||
| Losartan Potassium | 124750-99-8 | In stock |
Characterised impurities
| Impurity | Chemical name | Pharmacopoeia |
|---|---|---|
| Impurity “C” | [2-butyl-5-chloro-1- [[2’-(1H-tetrazol-5- yl)biphenyl-4-yl] methyl]-1H-imidazol- 4-yl]methanol | BP/EP/ UDMF |
| Impurity “D” | 2-butyl-4-chloro-1H- imidazole-5- carbaldehyde | BP/EP |
| Impurity “E” | 5-(4’- methylbiphenyl-2- yl)-1H-tetrazole | BP/EP |
| Impurity “F” | 5-[4’-[[2-butyl-4- chloro-5-[[(1- methylethyl)oxy] methyl]-1H-imidazol- yl]methyl]biphenyl- 2-yl]-1H-tetrazole | BP/EP |
| Impurity “G” | Triphenylmethanol [2-butyl-4-chlkoro-1- | BP/EP |
| Impurity “H” | [[2’-[2- (triphenylmethyl)-2H -tetrazol-5- yl]biphenyl-4- yl]methyl]-1H- imidazol-5- yl]methanol | BP/EP |
| Impurity "I" | 5-[4'-[[2-butyl-4- chloro-5- [[(triphenylmethyl]o xy]-methyl]-1H- imidazol-1- yl]methyl]biphenyl- 2-yl]-1H-tetrazole | BP/EP |
| Impurity “J” | [2-butyl-4-chloro-1- [[2’-(1H-tetrazol-5- yl)biphenyl-4-yl] methyl]-1H-imidazol- 5-yl]methyl acetate | BP/EP/ USDMF |
| Impurity “K” | 2-butyl-4-chloro-1- [[2’(1H-tetrazol-5- yl)biphenyl-4-yl] methyl]-1H-imidazol- 5-carbaldehyde | BP/EP/ USDMF |
| Impurity “M” | [2-butyl-1-[[2’-[2-[[2- butyl-4-chloro-1-[[2’- (1H-tetrazol -5-yl) biphenyl-4- yl]methyl]1H- imidazol-5- yl]methyl]2H- tetrazol-5- yl]biphenyl-4- yl]methyl]-4-chloro- 1H-imidazol-5- | (EP) |
| Condense d Mass Losartan | yl]methanol 4’-((2-butyl-4-chloro- 5-formyl-1H- imidazol-1- yl)methyl)-[1,1’- biphenyl]-]2- carbonitrile | IHT |
| N-Nitroso diethyl amine (NDEA) | N-Nitroso diethyl amine | IHT |
| NDMA Methyl | Nitrosodimethylami 5-(4'-((2-butyl-4- chloro-5- (methoxymethyl)-1H | IHT IHT |
| ether Azide impurity of BCFI | -imidazol-1- yl)methyl)[1,1'- biphenyl]-2-yl)-1H- tetrazole 5-(Azidomethyl)-2- butyl-4-chloro-1H- imidazole | IHT |
| Azide impurity of OTBB | 2-[4- (Azidomethyl)phenyl ]benzonitrile | IHT |
| Diphenyl Related Impurity | (([1,1’-biphenyl]-4,4’- diylbis(methylene))bi s(2-butyl-4-chloro- 1H-imidazole-1,5- diyl))dimethanol | IHT |
| "Azide" impurity of Losartan | 5-[4'-[[5- (azidomethyl)-2- buttyl-4-chloro-1H- imidazole-1- yl]methyl[1,1'- biphenyl]-2-yl]-2H- tetrazole | IHT |
| "Azide" impurity of Losartan Intermedia te-I Dibromo OTBN "Amine" impurity of Losartan | 4'((5-Azidomethyl)-2- butyl-4-chloro-1H- imidazol-1- yl)methyl-[1,1'- biphenyl-2- carbonitrile 2'-Cyano-4- dibromomethyl)biph enyl 5-(4-((5- (aminomethyl)-2- butyl-4-chloro-1H- imidazol-1- yl)methyl)-[1,1- biphenyl]-2-yl)-1H- tetrazole | IHT IHT |
| NDBA | Nitrosodibutylamine | IHT |
| Intermedia te-I | 4’-((2-butyl-4-chloro- 5-(hydroxyl methyl)1H-imidazol- yl)methyl)biphenyl- 2-carbonitrile | IHT |
| Impurity “A” | (trifluoromethyl)anili | BP/US P |
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