Linagliptin

Patent status

Patent information is provided for orientation only - verify independently.

Route - KSMs and intermediates

1. KSM3-Methyl-3,7-dihydro-1H-purine-2,6-dione1076-22-8
2. KSM1-bromobut-2-yne3355-28-0
3. KSM2-(Chloromethyl)-4-methylquinazoline109113-72-6
4. KSM(R)-3-(tert-Butoxycarbonylamino)piperidine309956-78-3
5. Intermediate8-Bromo 3-Methylxanthine93703-24-3
6. Intermediate8-bromo-7-(but-2-yn-1-yl)-3-methyl-Xanthine666816-98-4
7. Intermediate8-bromo-7-(but-2-yl)-3-methyl-1-((4- methylquinazolin-2-yl)-3-methyl xanthine853029-57-9
8. IntermediateBoc Linagliptin668273-75-4

Impurity and working standards - ready stock

Structure	Standard	CAS	Availability
	D-glutamic acid	6893-26-1	In stock	+ add