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Irbesartan

Human API

Route - KSMs and intermediates

  1. KSMCyclopentanone120-92-3
  2. KSMValeroyl Chloride638-29-9
  3. KSM2'-Cyano-4-bromomethyl biphenyl114772-54-2
  4. Intermediate1-Aminocyclopentane nitrile hemioxalate

Characterised impurities

ImpurityChemical namePharmacopoeia
Impurity “D”2-n-Butyl-4- spirocyclopentane- 2-imidazolin-5-one hydrochlorideIHT
Impurity “A” /Related Compound “C”3-Amino-6-(2,3- dichloro phenyl)-1,2,4- triazine-5(4H)-one.BP/EP
Impurity “D”6-(2,3- Dichlorophenyl)-1,2, 4-triazine- 3,5(2H,4H)-dioneBP/EP
Impurity “G”6-(2,4- dichlorophenyl)-1,2, 4-triazine-3,5- diamineEP

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