PRODUCT CATALOG
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Febuxostat
Human APIstandards in stock
Route - KSMs and intermediates
- KSM4-Hydroxybenzonitrile767-00-0
- KSMEthyl acetoacetate141-97-9
- KSMIsobutyl bromide78-77-3
- Intermediate4-Hydroxythiobenzamide25984-63-8
- IntermediateEthyl-2-( 4-hydroxy phenyl)-4-methyl-1,3-thiazole-5- carboxylate #REF!161797-99-5
- IntermediateEthyl-2-(3-formyl-4-isobutoxyphenyl)-4- methylthiazole-5- carboxylate161798-03-4
- IntermediateFebuxostat Sodium
Impurity and working standards - ready stock
| Structure | Standard | CAS | Availability | |
|---|---|---|---|---|
| 4-Hydroxvbenzonitrile(4- HBN) | 99-96-7 | In stock | |
 | 4-Hydroxlrhiobenzamide(4- | 25984-63-8 | In stock | |
 | HTB) Ethyl-2-(4-hydroxyphenyl )- 4-methyl- 1,3-thiazole-5- carboxylate(HPTE) | 161797-99-5 | In stock | |
 | Ethyl-2-(3-fomyl-4- hvdloxyphenyl)--1- methylthiazole-5-carboxylate (FPTE) | 161798-01-2 | In stock | |
 | Ethyl-2-(3-fonnyl-4- isobutoxyphenyl) -4- metlrylthiazole- 5-carboxylare (IPTE) | 161798-03-4 | In stock | |
 | 2-(3-cyano-4-isobutoxy phenyl )-4- methylthiazole-5- carboxylic acid | 144060-53-7 | In stock | |
 | 2,4-Dichloro-5- sulfamoylbenzoic acid | 2736-23-4 | In stock | |
| Impurity-A | 161798-03-4 | In stock |
Characterised impurities
| Impurity | Chemical name | Pharmacopoeia |
|---|---|---|
| Isobutanol | 2-Methyl-1-Propanol | IHT |
| Sec-Butyl bromide 4- Hydroxybe nzamide / p- Hydroxybe nzamide | 2-Bromo butane Hydroxybenzamide Hydroxybenzamide | IHT IHT |
| Hydroxy Phenyl Thiazole Acid (HPTA) | 2-(4- Hydroxyphenyl)-4- methylthiazole-5- carboxylic acid | IHT |
| Hydroxy phenyl Thiazole ester (HPTE) | Ethyl-2-(4- hydroxyphenyl)-4- methyl-1,3-thiazole- 5-carboxylate | IHT |
| FPTA | 2-(3-Formyl-4- hydroxyphenyl)-4- methyl-1,3-thiazole- 5-carboxylic acid | IHT |
| FPTE | Ethyl-2-(3-formyl-4- hydroxyphenyl)-4- methylthiazole-5- carboxylate | IHT |
| sec-butyl phenyl thiazole ester Des Cyano Ethyl Ester | Ethyl 2-(4-Sec- butoxy)-3- formylphenyl)-4- methylthiazole-5- carboxylate Ethyl-2-(4- isobutoxyphenyl)-4- | IHT |
| Impurity (o-Alkyl HPTE) Des-Cyano Febuxosta t Impurity | methylthiazole-5- carboxylate 2-(4- isobutoxyphenyl)-4- methylthiazole-5- carboxylic acid | IHT IHT |
| IPTE | Ethyl-2-(3-formyl-4- isobutoxyphenyl)-4- methylthiazole-5- carboxylate | IHT |
| Impurity B / Sec-Butyl Ether Impurity | 2-(4-sec-Butoxy)-3- cyanophenyl)-4- methylthiaszole-5- carboxylic acid | IHT |
| Impurity A 4-HTB | Ethyl-2-(3-formyl-4- isobutoxyphenyl)-4- methyl-1,3-thiazole- 5-carboxylate 4-Hydroxy thiobenzamide (4- | IHT IHT |
| IMP-E (CPTE) | HTB) Cyano phenyl thiazole ester (CPTE) impurity E | IHT |
| IMP-C (Oxime Ester) | Impurity C / Oxime Ester | IHT |
| Febuxosta t Sodium | Febuxostat Sodium | IHT |
| Dialkyl impurity Dialkyl cyano impurity Ethyl-2- chloroacet oacetate | Isobutyl-2(3-formyl- isobutoxyphenyl)-4- methylthiazole-5- carboxylate Isobutyl-2-(3-Cyano- isobutoxyphenyl)-4- methylthiazole-5- carboxylate Ethyl-2-chloro-3- oxobutanoate | IHT IHT IHT |
| IMPURITY “A” | 5-Methyl-N-[2-(4- sulphamoylphenyl)- ethyl]pyrazine-2- carboxamide | EP/USP |
| Impurity “B” | cyclohexanamine | EP |
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