PRODUCT CATALOG
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Amlodipine
Human APIstandards in stock
Route - KSMs and intermediates
- KSMEthyl 4-Chloro Acetoacetate638-07-3
- KSMOrtho Chloro Benzaldehyde89-98-5
- KSMMethyl amino crotonate14205-39-1
- IntermediatePhthaloyl Amlodipine88150-62-3
Impurity and working standards - ready stock
| Structure | Standard | CAS | Availability | |
|---|---|---|---|---|
 | Hydroxy Ethyl Phthalimide(HEP) | 3891-07-4 | In stock | |
| Phthaloyl Amlodipine (PAML) | 88150-62-3 | In stock | |
 | Amlodipine Base | 88150-42-9 | In stock | |
 | Amlodipine Besylate | 111470-99-6 | In stock |
Characterised impurities
| Impurity | Chemical name | Pharmacopoeia |
|---|---|---|
| Impurity "D" i.e. Related compound "A" | 3-ethyl-5-methyl-2- [(2-aminoethoxy) methyl]-4-(2- chlorophenyl)-6- methylpyridine-3,5- dicarboxylate | BP/EP/ USP |
| Impurity "E" | 3,5-dimethyl(4RS)-4- chlorophenyl)-2[(2- amino ethoxy)methyl]-6- methyl-1,4- dihydropyridine-3,5- dicarboxylate | BP/EP |
| Impurity "F" | 3-Methyl 5-methyl (2-chlorophenyl)-6- methyl-2-[[2- [(2- aminoethoxy)methyl ]-1,4- dihydropyridine-3,5- dicarboxylate (Amlodipine Dimethyl Ester) | BP/EP |
| Impurity "G" | dimethyl-4-(2- chlorophenyl)-2,6- dimethyl-1,4- dihydropyridine-3,5- dicarboxylate | BP/EP |
| “Free Base ” | (RS)-3-ethyl 5- methyl 2-[(2- aminoethoxy) methyl]-4-(2- chlorophenyl)-6- methyl-1,4- dihydropyridine-3,5- | IHT |
| “BSEE” “BSME” | dicarboxylate Benzene sulphonic acid ethyl ester Benzene sulphonic acid methyl ester | USP USP |
| BSIPE/Ben zene impurity Related compound “B” | Benzene sulphonic acid Isopropyl Ester (3-Ethyl-5-methyl-4- (2-chlorophenyl)-6-- methyl-2-({2-[2- methylcarbamoyl) benzamido]ethoxy} methyl)-1,4- dihydropyridine-3,5- dicarboxylate) | USP USP |
| EPEA | Ethyl-4-[2- (Phthalimido)ethoxy] acetoacetate | IHT |
| MAC HEP- Intermedia te DHA/Arten imol/ | Methyl-3-amino crotonate (MAC) N-(2-hydroxyethyl) phthalimide (3R,5aS,6R,8aS,9R,1 0S,12R,12aR)- Decahydro-3,6,9- trimethyl-3,12- | IHT IHT IHT |
| Artenimol um | epoxy-12-H- pyrano[4,3-j]-1,2- benzodioxepin-10-ol | - |
| Artemisini n | (3R,5aS,6R,8aS,9R,12 S,12aR)-Octahydro- 3,6,9-trimethyl-3,12- epoxy-12H- | IHT |
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